|
KMID : 0391519960030020105
|
|
Journal of the Korean Child Neurology Society
1996 Volume.3 No. 2 p.105 ~ p.115
|
|
|
99mTc-HMPAO SPECT Study in Infantile Spasm
|
|
안여현
김영희/최승희/김병주/박기원/우영종
|
|
|
Abstract
|
|
|
To evaluate the clinical usefulness of 99mTc-HMPAO single photon emission computed tomography (SPECT) study in predicting the outcomes of West syndrome, clincial profiles including CT/MRI, EEG, SPECT findings at the onset of spasms and
developmental
outcome and seizure control after ACTH and other antiepileptic treatment were investigated in 10 infantile spasm patients (male 7. female 3). CT/MRI revealed brain abnormalities in 6 cases (4 diffuse cortical atrophy, 2 tuberous sclerosis). SPECT
showed
hypoperfusion in the frontal or temporal areas in 5 cases. Two cases with normal CT/MRI, and SPECT findings had normal development and no seizure after ACTH treatment. Two with normal CT/MRI and abnormal SPECT showed developmental delay and
seizures on
follw-up. Two three cases with abnormal Ct/MRI and normal SPECT showed developmental delay and 2 of them had no seizure and one became Lennox-Gastaut syndrome. All 3 cases with abnormal Ct/MRI, SPECT showed developmental retardation and
intractable
epilepsy. Our study indicates that the normal SPECT finding should be included in the criteria for the definition of crptogenic infantile spasm and might might have some role in predicting outcomes outcomes even in the symptomatic group.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|